Abstract In all infections, when you are in the acute phase
rise of the family Ig antibodies
M M and remain elevated for 6-12 weeks -
After this period, the test of Ig M M will be negative. The levels of antibody Ig G G remain present for the rest of our lives. In most people with ME / CFS Fibromyalgia but also healthy people when they make the analysis of viral realize they have found the antibody Ig G G for many viruses including EBV and CMV HHV-6, then he is told by the doctor who had an infection in the past and that now is not 'active. Sure you can do to lters test such as PCR, but they are still unreliable for a variety of reasons, and testing of Ig M M will not be positive in the vast majority of those with viral infections reactivated. there a medical test to show that if the IGG rise means that the virus has been reactivated? A successful experiment. A doctor in my city 'for years is studying multiple cases of people coming to his studio with various disorders (especially neurological) that they could not solve. Intrigued, beginning 'to study it and know' that the majority of patients had IgG antibodies (each of different viruses, but most of the varicella) tall. Then there was the question, not 'that the ascent of the IGG (showing that an infection and' past) indicates a viral reactivation? To demonstrate this, 'to every person who took the chicken pox, he did make the IgM and IgG antibodies and the same people who over time they got sick of varicella-zoster (the virus reactivated) did make the determination of the IGM and IGG. It 'that were absent IGM while the patient was in the acute phase of infection and number of IgG had risen enormously over the analysis had chickenpox when he was the first time. All this 'proof that there can' be a reactivation of the same virus and that, even if the IGM by the analysis are negative and the IGG are: not to say that the virus does not and 'active. Ecco degli studi americani che condividono questo pensiero. — "Ricerca sul Viral e infezioni sensibili agli antibiotici in CFS/FMS." Sidebar 1 - ricerca sulle infezioni virali e antibiotici di sensibili in CFS/FMS
• Uno studio di Dylewski et sul New England Journal of Medicine dimostra che nel sistema immunitario compromessi pazienti, come avviene nella CFS/FMS, infezioni attive correlare con altezze di anticorpi IgG senza elevazioni di anticorpi IgM e che una mancanza di elevazione della IgM non è utile in questi pazienti come un way to rule out active infection. must be maintained a high clinical suspicion and application of anti-infective treatment should be based on high levels of IgG. 22
• In addition to mycoplasma, numerous studies have shown other bacterial and viral infections such as EBV, CMV, HHV-6 and enterovirus in CFS and FM patients that cause or contribute to symptoms. The research also shows that these infections are present and active infection correlates with high IgG, despite the lack of IgM antibodies. 22-33 23-33 30,34,35 cause of immune dysfunction seen in CFS, there may be a lack of IgG antibodies present despite the presence of active infection. As with mycoplasma infections (see below), because these infections are generally acute, but rather a reactivation of old infection, an elevation of IgM antibodies is not usually seen with active infections of EBV, CMV, HHV-6 , Borrelia (Lyme) and enterovirus.
• Immune suppressed patients have also been shown to be helped by antiviral therapy in a series of studies. 36-40
• It is clear that most infections are present in patients with CFS / FMS. For example, a study found that 52% of CFS patients had active mycoplasma infection, 30.5% had active infection of HHV-6 and 7.5% had Chlamydia pneumonia infection vs only 6%, 9% and 1% of healthy people , respectively. They conclude, "The results indicate that a large subset of CFS patients show infection (s) bacterial or viral infection, and these infections may contribute to the severity of the signs and symptoms found in these patients." 41
Unfortunately, despite all data to the contrary, most physicians are not familiar with the research and still mistakenly think that a negative test with IgM antibodies confirms that there is no active infection.
Let's look at some viruses in patients with ME / CFS and possible cure.
HHV-6
A viral infection of HHV-6 is reactivated in many patients with chronic fatigue syndrome. A study in the Annals of Internal Medicine found 70 percent of CFS patients had active infection of HHV-6 . another study of HHV-6 in CFS patients, 89 percent at very high HHV-6 IgG antibody in PBS and above were found to have active infections in cell culture. 42 To compare, most healthy adults with an older, inactive infection levels are 1: 40 to 1: 160. Although not all studies were able to document infections, such as Harvard and CFS expert Professor Anthony Komaroff notes in his recent review of "the great majority of studies have found evidence of active replication of HHV-6 more often in patients with CFS than in healthy control subjects. 43 In
When HHV-6 is present, seems to involve natural killer cells of the immune system which are fundamental in the fight against infections and are often malfunction in CFS. Natural killer cell function is described in what is called lytic unit - which means the ability of cells to lyse or break down, the foreign invaders. The average person has a drive level of lytic 20 to 250, with more than 80 percent of healthy people, having more than 40 units. However, in people with CFIDS, the average natural killer lytic unit is just 12 units. With your immune system is so low, then reactivated HHV-6 may also cause reactivation of Epstein Barr virus. Furthermore, both EBV and HHV-6 can suppress immune function and HHV-6 can suppress your body's ability to combat fungal infections / yeast as well.
Until recently, there was no readily available treatment for HHV-6. Even if it is related to other herpes viruses, is resistant to acyclovir (Zovirax), Valtrex, famciclovir (Famvir) and other antiviral drugs that are commonly used for herpes infections of HHV-6. Fortunately, there is a new and promising oral antiviral called Valcyte, which has shown in early studies to be very beneficial in CFS patients who have the virus HHV-6 and EBV. Unfortunately, this drug can have significant side effects, even if it does not cause problems in most CFS patients and is very expensive. If you have a medical open-minded and are interested in exploring the Valcyte treatment, the information in Sidebar 2 may be useful to your doctor.
Sidebar 2 - diagnosis and treatment of reactivated HHV-6 infection in CFS
In a recent study by Professor Jose Montoya of Stanford University, CFS patients were treated with a new antiviral drug Valcyte if they had high IgG test for HHV-6 and EBV and had at least four of the following symptoms, impaired functioning cognitive processing speed slowed down, sleep disorders, deficits in short-term memory, fatigue and symptoms consistent with depression. In their first study of 12 patients, 9 to 12 (75%) patients "experienced near resolution of their symptoms. Allowing them to return to all activities of the workforce or full time in nine patients with a symptomatic response to treatment, EBV VCA IgG titles dropped from 1:2560 to 1:640 and IgG HHV-6 bonds fell from an average of 1:1280 to 1:320 ... serious adverse events were not observed among 12 patients. 44
I had the pleasure of speaking with Professor Montoya in January 2007 for further details on his treatment protocol. In CFS patients whose symptoms began with a flu-like illness and have at least a level of IgG antibodies to EBV VCA at least 1:640 plus HHV-6 IgG antibody of 1:640 (PBS or whether EBV is at least 1280) which he regards as follows (now use the test parameters of the blood observed earlier in this article):
1. Valcyte 900 mg 2 x day is given for 3 weeks,
2. Valcyte 900 mg x 1 day is given for 23 weeks.
for monitoring of toxicity (which is not found to be a problem for CFS patients), he performs the following tests: CBC
and chemical (BUN, Cr, ALT, AST) twice a week for three weeks, then once a week for three weeks, then every other week for three weeks and then monthly while on treatment.
He avoids using Valcyte in those with severe neuropathic pain (nerve) in their hands, as well as in patients with poor kidney function or who have white blood cell counts less than 3,500, such as potential toxicity is bone marrow suppression. He found that all patients who initially improved their symptoms flared from about the second to fourth weeks of treatment, often leaving their home for the same period of two weeks. Most noticed significant improvement after about three months in treatment. Patients who have spoken with who have taken very welcome, but few have developed recurrent symptoms when they stopped the drug after six months and are considering re-treatment. Although there is the potential toxicity of this drug, current experience suggests that it was not a serious problem of population of CFS. In our experience, those treated with the "SHINE Protocol" in addition to Valcyte often do not get the initial exacerbation of symptoms. can take 4 months to start seeing the benefit.
This treatment is very promising with the primary factor currently limiting its cost. costs of sixty 450 mg tablets (a one month supply) ~ $ 2,000 rebate to consumers Drugs (1-323-461-3606) and is available from Canada by mail for $ 1,500. This makes the 6 month cost $ 10,000 to 13 ~, 000. Prescription insurance usually covered the cost of the drug.
Professor Montoya has shown that a group of CFS patients with evidence of chronic viral infections with HHV 6 improved significantly with 6 months of the new antiviral Valcyte. Our experience now with 100 patients who have crossed the Valcyte treatment at the
fibromyalgia and fatigue centers showed that ~ 70% of these have improved dramatically. Some are healed. I think this treatment is a dramatic leap forward for a significant subset of those suffering with CFS and fibromyalgia. See
antivirals and immune boosters natural .
EBV and CMV The roles of EBV (Epstein Barr Virus) and CMV (cytomegalovirus) in CFIDS, also are unclear. is not uncommon for the levels of antibodies to these viruses also be elevated in people with chronic fatigue syndrome. However, we do not know whether this elevation reflects old inactive infection to verses from an infection with these viruses. Given the results with HHV-6 and lower levels of EBV antibodies after treatment, are inclined to believe that reactivation occurs with these viruses as well. As discussed in reference to infection HHV-6, have not found the antiviral Valtrex to be useful to treat the symptoms of CFS and no longer required. Valcyte still very promising and is more effective against HHV-6, CMV and EBV. Like HHV-6 seems to trigger the reactivation of EBV, which can suppress the infection HHV-6 is sufficient to allow the organism to overcome the EBV infection as well.
Valcyte
Besides, there are also a number of other treatments that may be useful in the fight against CMV, HHV-6 and other infections.
For all natural antiviral and chemicals used in American protcolli click HERE How can you tell if you need these treatments? If you need it the following symptoms persist:
| | Flu-like symptoms mainly with debilitating fatigue and little or no pain or fever. People with these symptoms are more likely to have underlying persistent viral infection such as HHV-6, CMV or EBV. In these cases, special blood tests for HHV-6 (HHV-6 IgG levels by IFA drawn and sent to laboratories for research labs to focus - if you consider Valcyte PBS or higher) and CMV (A CMV IgG-Valcyte consider whether 4.0 or higher) may help to identify who is a candidate for antiviral Valcyte
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| | A temperature over 98.6 ° F - 99 ° F even - and / or pulmonary congestion, sinusitis, a history of bad reactions to several antibiotics several (person wrongly this reaction "die-offs as a allergic reaction) , scalp wounds and scabbing other chronic bacterial infections. People with these symptoms seem to be more likely to have bacterial infections, mycoplasma or chlamydia responding special antibiotic. |
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From: http://www.endfatigue.com/health_articles_f-n / Infections-treating_hidden_viral_infections_cfs.html
Abstract . I heard only a few days ago that all the associations for rare diseases, patients and supporters have joined together to send a joint letter to all regions to seek recognition and allocation of a Regional Code of Exemption for Rare Diseases not yet included in Annex 1 of Decree 279/01. And that this project will end 'on 28 febbraio.Cosi we are to actively participate and collect signatures for the encefalomielte myalgia syndrome chronic fatigue, fibromyalgia and sensitivity' multiple chemical. 
For two and a half years after having been diagnosed by unconventional 
My experience . In these years of illness, I understood what life does not count workers occupying the position or the money you earn, 'cause in a moment, just a health problem not solved and you can' lose it all. It 's not the bank account of a person or position social make her be an important and special but rather the 'way of thinking and behaving and to love others .... 
